Walked past this on 6th St, just east of the Bowery. It looks like it's been there a while, but I've never noticed it before. The wall it's on is part of a games store, so I suppose they put it up.
Oh! Why yes, it's a real thing:
Nintendo was founded in 1889 as Nintendo Koppai by craftsman Fusajiro Yamauchi and originally produced handmade playing cards. After venturing into various lines of business during the 1960s, Nintendo distributed its first console, the Color TV-Game, in 1977.